LL-37 is the active fragment of human cathelicidin, an antimicrobial peptide the immune system already produces. It disrupts bacterial membranes and biofilms, neutralizes endotoxin, and modulates wound-healing responses including angiogenesis and re-epithelialization. That pairing of antimicrobial punch and repair signaling is why research attention keeps landing on stubborn infections and chronic wounds.
- The active fragment of human cathelicidin, an antimicrobial peptide the body already produces.researchdosing
- Disrupts bacterial membranes and biofilms, the structures that let infections shrug off antibiotics.PubMed
- Neutralizes endotoxin, a separate mechanism from straight bacterial killing.PubMed
- Modulates wound-healing responses including angiogenesis and re-epithelialization, which is why it shows up in chronic wound research.researchdosing
- Studied for stubborn biofilm infections and chronic wounds, not as a replacement for antibiotics where those are indicated.thepeptidereport