Selank is a synthetic tuftsin analog developed in Russia, where it is an approved pharmaceutical for anxiety disorders, a rare thing for a research peptide. It modulates GABAergic and serotonergic systems, inhibits enkephalin-degrading enzymes, and stimulates BDNF and NGF. The source describes the effect as clear-headed calm, though mild sedation is listed among reported effects. No Western clinical trial has completed, so the interest rests on the Russian record plus the mechanism.
- Approved in Russia for anxiety disorders, giving it a national regulatory record almost no research peptide has.Russian approval
- A tuftsin analog that modulates GABAergic and serotonergic systems and blocks enkephalin-degrading enzymes.PubMed: Selank
- Stimulates BDNF and NGF, the two growth factors at the center of neuroplasticity research.PubMed: Selank
- Reported effects are described as clear-headed calm rather than sedation.researchdosing
- Reported as generally well tolerated, with mild sedation or relaxation the usual effects, headache noted rarely, and no addiction or withdrawal reported.researchdosing