CJC-1295 + Ipamorelin

Two GH pathways, one pulse. No cortisol, no appetite bump.

GHRH and ghrelin receptors hit together in one preparation
Stronger combined pulse than either compound alone
No cortisol or appetite increase reported

Studied for Sleep qualityRecoveryBody composition

≥99% purity HPLC-tested Growth Hormone Best seller

Size

$74per vial

Free shipping over $200 · $10 flat otherwise · ships cold from the USA

Full research summary5 citations

A pre-mixed GHRH plus GHRP blend: CJC-1295 (No DAC) works on GHRH receptors while ipamorelin activates GHS-R1a ghrelin receptors. Two pathways firing together produce a synergistic GH pulse stronger than either compound alone, and the guide describes that pulse as arriving without increasing cortisol or appetite.

Two receptor pathways in a single preparation: CJC-1295 (No DAC) on GHRH receptors, ipamorelin on GHS-R1a ghrelin receptors.Peptide Guide p. 28
The combined pulse is described as stronger than either compound alone, and as occurring without increasing cortisol or appetite.Peptide Guide p. 28
GHRH promotes slow-wave sleep, which is why deeper sleep is the first change reported at 1-2 weeks, with recovery and energy at 4-6 weeks and body-composition change at 8-12 weeks.Peptide Guide p. 28
Women produce about 3x the GH of men yet show similar IGF-1.Span 2000
Oral estrogen blunts GH-driven IGF-1; transdermal does not.Weissberger 1991

Storage & handling

Freeze-dried at -4F; reconstituted 36-46F and best used within 28 days, after which potency gradually fades over about 4-6 weeks (structure-based estimate, no published data).

Research cautions

Active malignancy is an absolute contraindication (GH and IGF-1 can promote tumor growth), and prolonged continuous combined GHRH plus GHRP exposure drives receptor desensitisation.

Storage & handling

Freeze-dried at -4F; reconstituted 36-46F and best used within 28 days, after which potency gradually fades over about 4-6 weeks (structure-based estimate, no published data).

Research cautions

Active malignancy is an absolute contraindication (GH and IGF-1 can promote tumor growth), and prolonged continuous combined GHRH plus GHRP exposure drives receptor desensitisation.

Shipping & payment

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This compound is supplied for laboratory research use only and is not for human or veterinary consumption. The research summarized here describes published third-party findings, not outcomes from Limitless Peptides, and is not dosing guidance or medical advice.