Epithalon is the Khavinson peptide built to switch on telomerase, the enzyme that keeps chromosome ends from fraying. Telomerase (hTERT) activation has been reported in rodent studies and in human cell lines, alongside normalisation of pineal function. It is the most-studied of the longevity bioregulators, though the clinical record is almost entirely Russian and CIS.
- Stimulates telomerase (hTERT) expression, with telomerase activation reported in rodent studies, and normalises pineal function.PubMed: Epithalon
- The telomerase effect has turned up in human cell lines as well as animals.Peptide Guide, evidence note
- Reported changes start with sleep and circadian rhythm in the first week or two.Peptide Guide, expected effects
- PCAC recommended it (as "epitalon") for the 503A bulks list 7 to 5 in July 2026, an advisory, non-binding vote.PCAC vote, Jul 2026
- Straight talk: it is the most-studied Khavinson peptide and still has no Western RCT, with much of the CIS clinical data falling short of ICH-GCP standards.Peptide Guide, warnings